학술논문

IgG4-related disease and small lymphocytic lymphoma.
Document Type
Article
Source
QJM: An International Journal of Medicine. Jul2023, Vol. 116 Issue 7, p523-524. 2p.
Subject
*MONOCLONAL gammopathies
*LYMPHOMAS
*IMMUNOGLOBULIN light chains
*PARANEOPLASTIC syndromes
Language
ISSN
1460-2725
Abstract
The kidney biopsy features and the radiologic involvement of typical organs (kidneys, prostate, aorta and pancreas)[2] were the key to IgG4-RD diagnosis. Although IgG4-RD can masquerade as cancer, IgG4-RD may be associated with lymphoma and co-exist in the same site of biopsy, as in our case.[3] A recent meta-analysis suggested that patients with IgG4-RD have a higher risk of overall cancer, especially pancreatic and lymphoma.[4] Conversely, malignancy may be associated with subsequent IgG4-RD development.[5] The underlying pathophysiological link of this association remains unclear. (B) Renal biopsy disclosing dense cellular infiltration with SLL (left) adjacent to severe pauci-cellular interstitial fibrosis related to IgG4-RD (right) (original magnification ×20, Hematoxylin Eosin Safran). [Extracted from the article]