학술논문

Ocular Syphilis as a Cause of Chronic Postoperative Uveitis Followed by a Localized Ocular Jarisch–Herxheimer-like Reaction.
Document Type
Case Study
Source
Ocular Immunology & Inflammation. Apr2023, Vol. 31 Issue 3, p649-652. 4p.
Subject
*SYPHILIS
*UVEITIS
*EYE inflammation
*NEUROSYPHILIS
*NERVE fibers
Language
ISSN
0927-3948
Abstract
The case draws attention to syphilis as a cause of chronic postoperative uveitis following cataract surgery and is the first to document transient worsening of ocular inflammation without systemic symptoms after initiation of treatment, suggesting a localized Jarisch–Herxheimer-like reaction. Case report. The average thickness of the retinal nerve fiber layer was used as an objective measure of intraocular inflammation. The patient's nerve edema worsened during a standard neurosyphilis treatment course and returned to normal several weeks after completion of therapy. Syphilis serologic testing should be strongly considered in the work-up for chronic postoperative uveitis. A localized ocular Jarisch–Herxheimer-like reaction may occur and should not detract from completion of neurosyphilis treatment. [ABSTRACT FROM AUTHOR]