학술논문
Association between Non Alcoholic Fatty Liver Disease and Severity of Coronary Artery Disease in Patients Aged 45 Years and Below with Acute Coronary Syndrome.
Document Type
Article
Author
Source
Subject
*FATTY liver
*CORONARY artery disease
*ACUTE coronary syndrome
*ST elevation myocardial infarction
*AGE factors in disease
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Language
ISSN
0973-709X
Abstract
Introduction: Coronary Artery Disease (CAD) is an important extrahepatic cardiovascular complication of Non Alcoholic Fatty Liver Disease (NAFLD). Aim: To determine the prevalence of NAFLD in young (=45 years) Acute Coronary Syndrome (ACS) patients, and to assess the association between severity of NAFLD and severity of CAD. Materials and Methods: This cross-sectional study was conducted from May 2017-April 2018, with a total of 85 patients. CAD severity was determined by coronary angiogram while its complexity by SYNTAX score. Fatty liver was diagnosed and graded by liver ultrasound examination. Results: The prevalence of NAFLD was 100%. Thirty-three (38.9%) had ST-Elevation Myocardial Infarction (STEMI), 32 (37.6%) had Non STEMI (NSTEMI) and 20 (23.5%) had unstable angina. There was no significant correlation between NAFLD steatosis grades and ACS subtypes (p=0.721), severity of CAD (p=0.822) and SYNTAX score (p=0.982). No association between NAFLD fibrosis score and ACS subtypes (p=0.232), severity of CAD (p=0.445) or SYNTAX score (p=0.839) were observed. Conclusion: The NAFLD was extremely prevalent in young ACS patients. However, no significant association between severity of NAFLD and severity of CAD was found. [ABSTRACT FROM AUTHOR]