부산대학교 도서관

Aims: To conduct a secondary analysis of the SAGE study to evaluate the association between glycaemic control and patient‐reported outcomes (PROs), in adults with type 1 diabetes (T1DM) across different age groups and regions. Materials and methods: SAGE was a multinational, cross‐sectional, observational study in adults with T1DM. Data were collected at a single visit, analysed according to predefined age groups (26‐44, 45‐64, and ≥65 years), and reported across different regions. PRO questionnaires were applied to assess hypoglycaemia fear (Hypoglycemia Fear Survey‐II), diabetes‐related distress (Problem Areas In Diabetes questionnaire), insulin treatment satisfaction (Insulin Treatment Satisfaction Questionnaire), and diabetes‐specific quality of life (QoL; Audit of Diabetes‐Dependent Quality of Life). Multivariable analysis was performed to evaluate the relationship between glycated haemoglobin (HbA1c) target achievement (<7% and individualised targets) with PRO scores. Results: The PRO scores showed relatively low levels of diabetes‐related emotional distress and fear of hypoglycaemia, moderate to high treatment satisfaction, and low diabetes‐related impact on QoL. Results were generally comparable across age groups with some regional variability. Achievement of the HbA1c <7% target was associated with less worry about hypoglycaemia, lower diabetes‐related emotional distress, higher insulin treatment satisfaction, and higher QoL. Achievement of individualised HbA1c targets was associated with lower diabetes‐related emotional distress and higher insulin treatment satisfaction. Conclusions: Better glycaemic control was most closely associated with low emotional distress due to diabetes and high patient‐reported insulin treatment satisfaction. [ABSTRACT FROM AUTHOR]