학술논문

Effects of Varying Case Definition on Carpal Tunnel Syndrome Prevalence Estimates in a Pooled Cohort
Document Type
article
Source
Archives of Physical Medicine and Rehabilitation. 95(12)
Subject
Neurosciences
Clinical Research
Neurodegenerative
Chronic Pain
Pain Research
Peripheral Neuropathy
7.3 Management and decision making
Management of diseases and conditions
Adult
Carpal Tunnel Syndrome
Construction Industry
Electrodiagnosis
Female
Health Care Sector
Humans
Male
Manufacturing Industry
Median Nerve
Middle Aged
Occupational Injuries
Prevalence
Reaction Time
Ulnar Nerve
Carpal tunnel syndrome
Diagnostic techniques and procedures
Rehabilitation
Standards
Clinical Sciences
Human Movement and Sports Sciences
Public Health and Health Services
Language
Abstract
ObjectiveTo analyze differences in carpal tunnel syndrome (CTS) prevalence using a combination of electrodiagnostic studies (EDSs) and symptoms using EDS criteria varied across a range of cutpoints and compared with symptoms in both ≥1 and ≥2 median nerve-served digits.DesignPooled data from 5 prospective cohorts.SettingHand-intensive industrial settings, including manufacturing, assembly, production, service, construction, and health care.ParticipantsEmployed, working-age participants who are able to provide consent and undergo EDS testing (N=3130).InterventionsNone.Main outcome measuresCTS prevalence was estimated while varying the thresholds for median sensory latency, median motor latency, and transcarpal delta latency difference. EDS criteria examined included the following: median sensory latency of 3.3 to 4.1 milliseconds, median motor latency of 4.1 to 4.9 milliseconds, and median-ulnar sensory difference of 0.4 to 1.2 milliseconds. EDS criteria were combined with symptoms in ≥1 or ≥2 median nerve-served digits. EDS criteria from other published studies were applied to allow for comparison.ResultsCTS prevalence ranged from 6.3% to 11.7%. CTS prevalence estimates changed most per millisecond of sensory latency compared with motor latency or transcarpal delta. CTS prevalence decreased by 0.9% to 2.0% if the criteria required symptoms in 2 digits instead of 1.ConclusionsThere are meaningful differences in CTS prevalence when different EDS criteria are applied. The digital sensory latency criteria result in the largest variance in prevalence.