학술논문

Safety and diagnostic efficacy of gadoteridol for magnetic resonance imaging of the brain and spine in children 2 years of age and younger.
Document Type
article
Source
Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 51(10)
Subject
Central nervous system
Children
Contrast
Diagnostic efficacy
Gadolinium-based contrast agent
Gadoteridol
Magnetic resonance imaging
Safety
Brain
Brain Neoplasms
Child
Preschool
Contrast Media
Gadolinium
Heterocyclic Compounds
Humans
Infant
Infant
Newborn
Magnetic Resonance Imaging
Organometallic Compounds
Retrospective Studies
Language
Abstract
BACKGROUND: Neonates and young children require efficacious magnetic resonance imaging (MRI) examinations but are potentially more susceptible to the short- and long-term adverse effects of gadolinium-based contrast agents due to the immaturity of their body functions. OBJECTIVE: To evaluate the acute safety and diagnostic efficacy of gadoteridol (ProHance) for contrast-enhanced MRI of the central nervous system (CNS) in children ≤2 years of age. MATERIALS AND METHODS: One hundred twenty-five children ≤2 years old (including 57 children