학술논문

Dietary prophage inducers and antimicrobials: toward landscaping the human gut microbiome.
Document Type
article
Source
Gut Microbes. 11(4)
Subject
Bacteriophage
antimicrobials
bactericidal
bacteroidetes
diet
firmicutes
flow cytometry
gut microbiome
prophage induction
stevia
Anti-Bacterial Agents
Bacteria
Diet
Feces
Food
Food Additives
Gastrointestinal Microbiome
Humans
Metagenome
Plant Extracts
Virus Activation
Language
Abstract
The approximately 1011 viruses and microbial cells per gram of fecal matter (dry weight) in the large intestine are important to human health. The responses of three common gut bacteria species, and one opportunistic pathogen, to 117 commonly consumed foods, chemical additives, and plant extracts were tested. Many compounds, including Stevia rebaudiana and bee propolis extracts, exhibited species-specific growth inhibition by prophage induction. Overall, these results show that various foods may change the abundances of gut bacteria by modulating temperate phage and suggests a novel path for landscaping the human gut microbiome.