학술논문
Neurodevelopmental delay in children exposed to maternal SARS-CoV-2 in-utero
Document Type
article
Author
Fajardo-Martinez, Viviana; Ferreira, Fatima; Fuller, Trevon; Cambou, Mary Catherine; Kerin, Tara; Paiola, Sophia; Mok, Thalia; Rao, Rashmi; Mohole, Jyodi; Paravastu, Ramya; Zhang, Dajie; Marschik, Peter; Iyer, Sai; Kesavan, Kalpashri; Borges Lopes, Maria da Conceição; Britto, José Augusto A; Moreira, Maria Elisabeth; Brasil, Patricia; Nielsen-Saines, Karin
Source
Scientific Reports. 14(1)
Subject
Language
Abstract
It is unclear if SARS CoV-2 infection during pregnancy is associated with adverse neurodevelopmental repercussions to infants. We assessed pediatric neurodevelopmental outcomes in children born to mothers with laboratory-confirmed SARS CoV-2 infection during pregnancy. Neurodevelopmental outcomes of in-utero exposed children were compared to that of pre-pandemic control children in Los Angeles (LA), CA, USA and Rio de Janeiro, Brazil. Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III), the gold standard tool for evaluating neurodevelopment until 36 months of age and Ages and Stages Questionnaires (ASQ-3), a frequently used screening instrument for evaluating neurodevelopment in this same age group were the assessment tools used. Developmental delay (DD) was defined as having a score