학술논문

Effect of Intravenous or Perivascular Injection of Synthetic Adrenocorticotropic Hormone on Stimulation Test Results in Dogs
Document Type
article
Source
Journal of Veterinary Internal Medicine. 31(3)
Subject
Veterinary Sciences
Agricultural
Veterinary and Food Sciences
Adrenocortical Hyperfunction
Adrenocorticotropic Hormone
Animals
Case-Control Studies
Dog Diseases
Dogs
Female
Hydrocortisone
Injections
Intravenous
Injections
Subcutaneous
Male
Hyperadrenocorticism
Endocrinology
Adrenal
Pituitary
Trilostane
Veterinary sciences
Language
Abstract
BackgroundStandard protocols for adrenocorticotropic hormone (ACTH) stimulation testing (ACTHst) often involve intravenous (IV) injection of corticotropin. ACTH might be unintentionally injected into the perivascular (PV) space.ObjectiveTo compare stimulation test results after IV and PV injections of ACTH.AnimalsTwenty privately owned dogs were studied: 10 healthy and 10 with trilostane-treated naturally occurring hyperadrenocorticism (HAC).MethodsProspective study. Each of 20 dogs underwent 2 ACTHst not