학술논문
Genetic variation in B cell–activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects
Document Type
article
Author
Kumar, Rajesh; Williams, L Keoki; Kato, Atsushi; Peterson, Edward L; Favoreto, Silvio; Hulse, Katie; Wang, Deli; Beckman, Kenneth; Thyne, Shannon; LeNoir, Michael; Meade, Kelley; Lanfear, David E; Levin, Albert M; Favro, David; Yang, James J; Weiss, Kevin; Boushey, Homer A; Grammer, Leslie; Avila, Pedro C; Burchard, Esteban G; Schleimer, Robert
Source
Journal of Allergy and Clinical Immunology. 130(4)
Subject
Language
Abstract
A BAFF polymorphism is associated with asthma exacerbations and serum BAFF levels. BAFF expression in vivo increases in natural rhinovirus infection. BAFF may play a role in airway antiviral immunity and impact asthma exacerbation rates.