학술논문

A whole-of-population study of term and post-term gestational age at birth and childrenʼs development
Document Type
Academic Journal
Source
BJOG: An International Journal of Obstetrics and Gynaecology. Sep 01, 2015 122(10):1303-1311
Subject
Language
English
ISSN
1470-0328
Abstract
OBJECTIVE: To examine the risk of poor child development according to week of gestation at birth, among children born ≥37 weeksʼ gestation. DESIGN: Population-based study using linked data (n = 12 601). SETTING: South Australia. POPULATION: All births ≥37 weeksʼ gestation. METHODS: Relative risks of developmental vulnerability for each week of gestation were calculated with adjustment for confounders and addressing missing information. MAIN OUTCOME MEASURES: Child development was documented by teachers during a national census of children attending their first year of school in 2009, using the Australian Early Development Index (AEDI). Children scoring in the lowest 10% of the AEDI were categorised as developmentally vulnerable. RESULTS: The percentage of children vulnerable on one or more AEDI domains for the following gestational ages 37, 38, 39, 40, 41, 42–45 weeks was 24.8, 22.3, 20.6, 20.0, 20.4 and 24.2, respectively. Compared with children born at 40 weeks, the adjusted relative risks [(95% confidence interval (CI)] for vulnerability on ≥1 AEDI domain were; 37 weeks 1.13 (0.99–1.28), 38 weeks 1.05 (0.96–1.15), 39 weeks 1.02 (0.94–1.12), 41 weeks 1.00 (0.90–1.11) and 42–45 weeks 1.20 (0.84–1.72). CONCLUSIONS: Children born at 40–41 weeksʼ gestation may have the lowest risk of developmental vulnerability at school entry, reinforcing the importance of term birth in perinatal care. Early term or post-term gestational age at birth can help clinicians, teachers and parents recognise children with potential developmental vulnerabilities at school entry.