부산대학교 도서관

Purpose: To investigate the efficacy of the combined phototherapeutic keratectomy (PTK) and peripheral anterior stromalpuncture (ASP) compared with that of PTK alone in patients with recurrent corneal erosion syndrome (RCES). Methods: The medical records of 25 patients (25 eyes) who underwent combined treatment of PTK and peripheral ASP forRCES from March 2016 to May 2017 were retrospectively reviewed. Twenty-three patients (23 eyes) treated with PTK alonefrom March 2015 to February 2016 served as a control group. All surgeries were performed by a single surgeon. This retrospectiveclinical study comprised 48 patients (48 eyes) who were followed up for more than 18 months. Clinical records ofage, sex, laterality, etiology of RCES, and history of recurrence after treatment were evaluated. Results: Twenty-five eyes were treated with combined PTK and ASP, and 23 eyes were treated with PTK only. The meanfollow-up period was 19.63 ± 2.97 and 19.75 ± 6.83 months, respectively. There were no differences in baseline parametersbetween the groups. In the combined treatment group, one patient experienced recurrence 6 months after the surgery. Inthe single treatment group, five patients showed recurrence at 4, 7, 8, 11, and 13 months after the surgery, respectively. Compared to the single treatment group, the combined treatment group showed significantly lower recurrence rate (p < 0.05). All recurred patients required no additional treatment except temporary therapeutic contact lenses and topical lubricants. Conclusions: Our findings suggest that combined treatment of PTK and peripheral ASP is effective in alleviation of symptomsand prevention of recurrence in refractory RCES compared with treatment using PTK alone.