학술논문

Clinical Features of Gastroduodenal Ulcers in Kidney Transplant Patients
Document Type
Journal Article
Source
Internal Medicine. 2023, 62(23):3437
Subject
Helicobacter pylori
cytomegalovirus
gastroduodenal ulcer
kidney transplantation
mycophenolate mofetil
solid organ transplantation
Language
English
ISSN
0918-2918
1349-7235
Abstract
Results Gastroduodenal ulcers were observed more frequently (6.5%) in kidney transplant patients than in CKD patients (2.1%) (p=0.026). Due in part to the lower median age in the kidney transplant ulcer group than in the CKD ulcer group (59 vs. 70 years old, p=0.016), the rates of atrophic gastritis and Helicobacter pylori infection were also lower in the kidney transplant ulcer group than in the CKD ulcer group. Significantly more kidney transplant patients were treated with acid secretion inhibitors than CKD ulcer patients (100% vs. 34.8%, p=0.0005). Peptic ulcers were observed frequently in kidney transplant patients, even though common risk factors for gastroduodenal ulcers other than immunosuppressive drugs were few. All kidney transplant patients were taking immunosuppressive medications, and tacrolimus, mycophenolate mofetil, and methylprednisolone were taken more frequently than others.