학술논문

A CASE OF RENAL CELL CARCINOMA WITH INFERIOR VENA CAVAL TUMOR THROMBUS WHICH THE REDUCTION OF TUMOR IN SPITE OF DRUG DISCONTINUANCE AFTER THE FULMINANT HEPATITIS ONSET WITH THE SUNITNIB / スニチニブによる劇症肝炎発症後,腫瘍縮小の継続を認めた腎癌下大静脈腫瘍塞栓の1例
Document Type
Journal Article
Source
日本泌尿器科学会雑誌 / The Japanese Journal of Urology. 2018, 109(2):102
Subject
Sunitinib
fulminant hepatitis
inferior vena caval tumor thrombus
スニチニブ
下大静脈腫瘍塞栓
劇症肝炎
Language
Japanese
ISSN
0021-5287
1884-7110
Abstract
A 70-year-old man presented with right renal cell carcinoma with inferior vena caval tumor thrombus into the right atrium. CT Scan presented local invasion and lymph node metastasis. We estimated inoperative case, so he was started sunitinib. After 5 month he had general fatigue and admitted to our hospital. He diagnosed serious adverse events of fulminant hepatitis and left ventricular systolic dysfunction and discontinued sunitnib. After drug discontinuance reduction of tumor and tumor thrombus were detected. 7-months later, we showed the increase of tumor and the improvement of the left ventricular systolic dysfunction. We performed right renal nephrectomy and it passes now in 14 months after surgery, but doses not show a recurrence, metastasis.