학술논문
Blood coagulation monitoring with thromboelastography in different traumatic brain injury rat models / 重症頭部外傷モデルにおけるThromboelastography（TEG）を用いた血液凝固モニタリング：Goal Direct Therapyを指向した実験的検討
Document Type
Journal Article
Author
Source
神経外傷 / Neurotraumatology. 2013, 36(2):149
Subject
Language
Japanese
ISSN
2434-3900
Abstract
Results: In the early phase (2.5 h) after injury, K-value, which indicates impairment of fibrinogenesis, was significantly higher in ASDH than in FPI (p<0.01). Moreover, MA (Maximal amplitude) and G value, which indicate the strength of platelet-fibrin interaction, were significantly lower in ASDH than FPI (p<0.05, respectively). Moreover, the Coagulation Index (CI), which indicates overall status of coagulation was the lowest in ASDH. Blood coagulation profiles of PBBI were similar to ASDH, although less severe. On the other hand, the peak of coagulopathy in FPI existed on later phase (24 h) after injury, and continued by the 7th day.