학술논문

A case of amebic colitis that developed after corticosteroid therapy in which perforation occurred during metronidazole treatment / ステロイド使用下で発症し治療にかかわらず消化管穿孔をきたしたアメーバ腸炎の1例
Document Type
Journal Article
Source
日本消化器病学会雑誌 / Nippon Shokakibyo Gakkai Zasshi. 2021, 118(5):455
Subject
アメーバ腸炎
免疫抑制
腸穿孔
Language
Japanese
ISSN
0446-6586
1349-7693
Abstract
Although amebiasis is usually asymptomatic, fulminant amebic colitis is associated with a high mortality rate. Here, we report the case of a patient with amebic colitis in which bowel perforation occurred despite treatment with metronidazole. A man in his 70s underwent steroid pulse therapy to treat serious acute hepatitis A. After corticosteroid therapy, he developed acute abdomen because of amebic colitis. We immediately administered metronidazole and his symptoms improved. After completing treatment, he developed colon perforation. Amebic colitis can progress to bowel perforation even after administering the appropriate medication, so this abdominal symptom requires careful attention.