학술논문
Do MYO9B genetic variants predispose to coeliac disease? An association study in a cohort of South Italian children
Document Type
Author abstract
Author
Source
Digestive and Liver Disease. March, 2007, Vol. 39 Issue 3, p228, 4 p.
Subject
Language
English
ISSN
1590-8658
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.dld.2006.12.009 Byline: G. Cirillo, M.R. Di Domenico, I. Corsi, T. Gagliardo, E.M. del Giudice, L. Perrone, C. Tolone Keywords: Association study; Children; Coeliac disease; MYO9B polymorphism Abstract: Coeliac disease is a complex disorder influenced by environmental and genetic factors. A genome wide linkage study identified the myosin IXB (MYO9B) as a gene possibly associated with coeliac disease. Recently, a Dutch study reported a strong association of a single SNP, rs 2305764, of MYO9B with coeliac disease. However, two successive studies carried out on British and Swedish/Norwegian cohorts reported lack of association of the MYO9B variant with coeliac disease. Author Affiliation: Department of Pediatrics "F. Fede", Second University of Naples, Via Luigi De Crecchio 2, 80138 Naples, Italy Article History: Received 20 July 2006; Accepted 11 December 2006