학술논문
Middle-term outcomes in renal transplant recipients with COVID-19: a national, multicenter, controlled study
Document Type
Report
Author
Oto, Ozgur Akin; Ozturk, Savas; Arici, Mustafa; Velioglu, Arzu; Dursun, Belda; Guller, Nurana; Sahin, Idris; Eser, Zeynep Ebru; Paydas, Saime; Trabulus, Sinan; Koyuncu, Sumeyra; Uyar, Murathan; Ural, Zeynep; Sadioglu, Rezzan Eren; Dheir, Hamad; Koc, Neriman Sila; Ozer, Hakan; Durak, Beyza Algul; Gul, Cuma Bulent; Kasapoglu, Umut; Oguz, Ebru Gok; Tanrisev, Mehmet; Kuzgun, Gulsah Sasak; Mirioglu, Safak; Dervisoglu, Erkan; Erken, Ertugrul; Gorgulu, Numan; Ozkurt, Sultan; Aydin, Zeki; Kurultak, Ilhan; Ogutmen, Melike Betul; Bakirdogen, Serkan; Kaya, Burcu; Karadag, Serhat; Ulu, Memnune Sena; Gungor, Ozkan; Bakir, Elif Ari; Odabas, Ali Riza; Seyahi, Nurhan; Yildiz, Alaattin; Ates, Kenan
Source
Clinical Kidney Journal. May, 2022, Vol. 15 Issue 5, p999, 8 p.
Subject
Language
English
ISSN
2048-8505
Abstract
Background. In this study, we evaluated 3-month clinical outcomes of kidney transplant recipients (KTR) recovering from COVID-19 and compared them with a control group. Method. The primary endpoint was death in the third month. Secondary endpoints were ongoing respiratory symptoms, need for home oxygen therapy, rehospitalization for any reason, lower respiratory tract infection, urinary tract infection, biopsy-proven acute rejection, venous/arterial thromboembolic event, cytomegalovirus (CMV) infection/disease and BK viruria/viremia at 3 months. Results. A total of 944 KTR from 29 different centers were included in this study (523 patients in the COVID-19 group; 421 patients in the control group). The mean age was 46 [+ or -] 12 years (interquartile range 37-55) and 532 (56.4%) of them were male. Total number of deaths was 8 [7 (1.3%) in COVID-19 group, 1 (0.2%) in control group; P = 0.082]. The proportion of patients with ongoing respiratory symptoms [43 (8.2%) versus 4 (1.0%); P < 0.001] was statistically significantly higher in the COVID-19 group compared with the control group. There was no significant difference between the two groups in terms of other secondary endpoints. Conclusion. The prevalence of ongoing respiratory symptoms increased in the first 3 months post-COVID in KTRs who have recovered from COVID-19, but mortality was not significantly different. Keywords: COVID-19, kidney transplantation, mortality, outcome, registry
INTRODUCTION Coronavirus disease 2019 (COVID-19) has rapidly turned into a global pandemic after emerging in China in December 2019. It has been shown that approximately 20% of COVID-19 patients have [...]
INTRODUCTION Coronavirus disease 2019 (COVID-19) has rapidly turned into a global pandemic after emerging in China in December 2019. It has been shown that approximately 20% of COVID-19 patients have [...]