학술논문
Vitamin D-receptor gene polymorphisms and bone density in prepubertal American girls of Mexican descent
Document Type
Academic Journal
Author
Source
The New England Journal of Medicine. July 10, 1997, Vol. v337 Issue n2, p77, 6 p.
Subject
Language
ISSN
0028-4793
Abstract
Variations in the gene for the vitamin D receptor appear to be linked to bone density in children. Researchers used CT scans to measure the density of the spine and thighbone in 100 Mexican-American girls and genetic analysis to determine which vitamin D receptor gene they had. Two gene types resulted in a 2% to 3% higher density in the thighbone and an 8% to 10% higher density in the spine. However, no gene type was associated with larger bones. Genetic analysis could reveal children who could be at risk of bone fractures later in life.