부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.clinimag.2006.07.004 Byline: Youko Idobe-Fujii (a), Nagako Ogi (a), Keiko Hosho (b), Masahiko Koda (b), Yoshikazu Murawaki (b), Yasushi Horie (c) Keywords: Hepatocellular carcinoma; Sarcomatous change; Interferon therapy; HCV Abstract: A patient was diagnosed with chronic hepatitis C at the age of 63 years. He achieved eradication of HCV via interferon (IFN). Eight years after, a hepatocellular carcinoma (HCC) was detected and treated through transarterial embolization and percutaneous ethanol injection therapy. After about 1 year, a large hypovascular tumor was detected. This tumor was surgically resected and diagnosed as an HCC with sarcomatous change. This is the first case of an HCC with sarcomatous change arising after a sustained response to IFN therapy. Author Affiliation: (a) Hitachi-kinen hospital, 1278-5, Yasugi-cho, Yasugi-shi, Shimane 692-0011, Japan (b) Second Department of Internal Medicine, Faculty of Medicine, Tottori University, Japan (c) Division of Pathology, Tottori University Hospital, Faculty of Medicine, Tottori University, Japan Article History: Received 15 June 2006; Accepted 20 July 2006