학술논문
Fighting antibiotic resistance in the intensive care unit using antibiotics
Document Type
Report
Source
Future Microbiology. March 2015, Vol. 10 Issue 3, p391, 16 p.
Subject
Language
English
ISSN
1746-0913
Abstract
ABSTRACT Antibiotic resistance is a global and increasing problem that is not counterbalanced by the development of new therapeutic agents. The prevalence of antibiotic resistance is especially high in intensive care units with frequently reported outbreaks of multidrug-resistant organisms. In addition to classical infection prevention protocols and surveillance programs, counterintuitive interventions, such as selective decontamination with antibiotics and antibiotic rotation have been applied and investigated to control the emergence of antibiotic resistance. This review provides an overview of selective oropharyngeal and digestive tract decontamination, decolonization of methicillin-resistant Staphylococcus aureus and antibiotic rotation as strategies to modulate antibiotic resistance in the intensive care unit.
Author(s): Nienke L Plantinga [sup.aff1] , Bastiaan HJ Wittekamp [sup.[*]] [sup.aff1] , Pleun J van Duijn [sup.aff1] , Marc JM Bonten [sup.aff1] KEYWORDS antibiotic resistance; antibiotic rotation; cycling; decolonization; intensive [...]
Author(s): Nienke L Plantinga [sup.aff1] , Bastiaan HJ Wittekamp [sup.[*]] [sup.aff1] , Pleun J van Duijn [sup.aff1] , Marc JM Bonten [sup.aff1] KEYWORDS antibiotic resistance; antibiotic rotation; cycling; decolonization; intensive [...]