학술논문

CD 200/CD 200R paired potent inhibitory molecules regulating immune and inflammatory response
CD 200/CD 200R paired potent inhibitory molecules regulating immune and inflammatory response. Part II. CD 200/CD 200R potential clinical applications
CD 200/CD 200R potential clinical applications
Document Type
TEXT
Source
Acta medica (Hradec Králové) | 2012 Volume:55 | Number:2
Subject
zvířata
antigeny CD--imunologie--terapeutické užití
autoimunitní nemoci--imunologie
nemoci centrálního nervového systému--imunologie
lidé
imunita
nádory--imunologie--terapie
transplantační imunologie
virové nemoci--imunologie
Language
English
Abstract
CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some. Many research projects are aimed to develop clinically valuable methods being based on the structure and function of these paired molecules. In this review, we would like to introduce CD200/CD200R functions in a clinical context.
Drahomíra Holmannová, Martina Koláčková, Kateřina Kondělková, Pavel Kuneš, Jan Krejsek, Ctirad Andrýs
Literatura 51