학술논문
Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males
Document Type
TEXT
Author
http://aut.nkp.cz/xx0101388; http://aut.nkp.cz/xx0043092; Jarkovský, J.; http://aut.nkp.cz/xx0101387; http://aut.nkp.cz/xx0070655; http://aut.nkp.cz/xx0142588; http://aut.nkp.cz/xx0079551; http://aut.nkp.cz/xx0101389; http://aut.nkp.cz/xx0137950; http://aut.nkp.cz/xx0142879; http://aut.nkp.cz/xx0054290; http://aut.nkp.cz/nlk20030128322
Source
Subject
Language
English
Multiple Languages
Multiple Languages
Abstract
J. Pařenica ... [et al.].
Obsahuje bibliografii a bibliografické odkazy
A high pulse pressure (PP) is a marker of increased artery stiffness and represents a well-e stablished independent predictor for cardiovascular morbidity and mortality. The objective of the research was to determine whether invasively measured central aortic PP was related to the presence and severity of coronary artery disease. In total 1075 consecutive stable male patients undergoing diagnostic coronary angiography with a preserved left ventricular function were included. Diseased coronary vessel (DCV) was defined by the presence of >50 % stenosis. Men were divided into 3 groups according to the increased value of PP. The average PP in the tertiles was 47.8±7.1 vs. 67.0±4.9 vs. 91.3±12.8 mm Hg (p<0,01). The si gnificant differences of DCV was found among tertiles (1.51±1.11 vs 1.80±1.04 vs. 1.99±0.98 DCV, p<0.01). Aortic PP together with age and hyperlipoproteinemia were found as factors with an independent relationship to DCV according to multivariate linear regression. In conclusions the increased value of aortic PP in the male population is independently connected with more severe atherosclerosis evaluated by the significant number of DCV.
Obsahuje bibliografii a bibliografické odkazy
A high pulse pressure (PP) is a marker of increased artery stiffness and represents a well-e stablished independent predictor for cardiovascular morbidity and mortality. The objective of the research was to determine whether invasively measured central aortic PP was related to the presence and severity of coronary artery disease. In total 1075 consecutive stable male patients undergoing diagnostic coronary angiography with a preserved left ventricular function were included. Diseased coronary vessel (DCV) was defined by the presence of >50 % stenosis. Men were divided into 3 groups according to the increased value of PP. The average PP in the tertiles was 47.8±7.1 vs. 67.0±4.9 vs. 91.3±12.8 mm Hg (p<0,01). The si gnificant differences of DCV was found among tertiles (1.51±1.11 vs 1.80±1.04 vs. 1.99±0.98 DCV, p<0.01). Aortic PP together with age and hyperlipoproteinemia were found as factors with an independent relationship to DCV according to multivariate linear regression. In conclusions the increased value of aortic PP in the male population is independently connected with more severe atherosclerosis evaluated by the significant number of DCV.