학술논문
Synthesis and chromatographic-separation of the stereoisomers of furnidipine
Document Type
PeerReviewed
info:eu-repo/semantics/article
TEXT
info:eu-repo/semantics/article
TEXT
Author
Source
Subject
Language
English
Spanish
Spanish
Abstract
The four stereoisomers of methyl tetrahydrofuran-2-ylmethyl 2,6-dimethyl-4-(o-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxilate (furnidipine), have been synthesized and separated by chiral chromatography using D-phenylglycine as chiral stationary phase. Enantiomeric purity of stereoisomers is determined by HPLC-CSP technique and configurations deduced via X-ray crystallography.