학술논문
Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs
Document Type
Article
Author
Matsuda, S.; Datta, D.; Mikami, A.; Woods, L.; Gilbert, J.A.; Bisbe, A.; Manoharan, R.M.; Kim, M.; Theile, C.S.; Guenther, D.C.; Jiang, Y.; Agarwal, S.; Maganti, R.; Schlegel, M.K.; Zlatev, I.; Charisse, K.; Rajeev, K.G.; Castoreno, A.; Maier, M.; Janas, M.M.; Manoharan, M.; Bala, S.; Liao, J.-Y.; Chaput, J.C.; Harp, J.M.; Egli, M.
Source
In: Journal of the American Chemical Society . (Journal of the American Chemical Society, 13 September 2023, 145(36):19691-19706)
Subject
Language
English
ISSN
15205126
00027863
00027863