부산대학교 도서관

Introduction: Assessment of maximal oxygen consumption (VO 2 max) is an important clinical tool when examining both healthy and unhealthy populations, as a low VO 2 max is associated with cardiovascular disease and all-cause mortality. Aim: This study investigated the accuracy of a non-exercise test for assessment of VO 2 max using seismocardiography (SCG). Methods: 97 participants (20–45 years, 50 males) underwent a nonexercise test using SCG at rest in the supine position (SCG VO 2 max) and a graded exercise test to voluntary exhaustion on a cycle ergometer with indirect calorimetry (IC VO 2 max). An interim analysis was applied after 50 participants had completed testing (SCG VO 2 max 1.0) allowing for the algorithm to be modified (SCG VO 2 max 2.1). Results: SCG VO 2 max 2.1 ($n=47$, test set) estimation was $3.5 \pm 1.8\ ml\cdot min^{-1}\cdot kg^{-1}\ (p < 0.001)$ lower compared to IC VO 2 max, with a Pearson correlation of $r=0.65 (p < 0.0001)$ and a standard error of estimate of 7.1 ml·min −1 ·kg −1 . The coefficient of variation between tests was $8\ \pm 1\%$. Conclusion: The accuracy of VO 2 max assessment using SCG requires further optimization prior to clinical application, as SCG VO 2 max was systematically lower than IC VO 2 max, and only a moderate correlation together with considerable variation were observed between tests.