학술논문
Electro-mediated damages in the narrowest pore of the voltage-gated K channels on skeletal muscle membrane
Document Type
Conference
Source
Proceedings of 17th International Conference of the Engineering in Medicine and Biology Society Engineering in medicine and biology Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference. 1:355-356 vol.1 1995
Subject
Language
Abstract
In this report the authors are trying to locate the conformational changes in membrane proteins, the voltage-gated K channels of skeletal muscle membrane, during exposure to a high voltage electric shock. Studies of the effects on channel functions correlated to protein structural residues extra- and intra-cellular, as well as intramembrane imply that for the narrowest pore the selectivity filter may be the most sensitive to the applied high voltage electrical field.