학술논문

Immunoglobulin-based hybrid targeted nanoagents for in vitro and in vivo multimodal imaging
Document Type
Conference
Source
2022 International Conference Laser Optics (ICLO) Laser Optics (ICLO), 2022 International Conference. :01-01 Jun, 2022
Subject
Photonics and Electrooptics
Power, Energy and Industry Applications
Nanoparticles
Proteins
In vivo
Protein engineering
Imaging
Medical treatment
Optics
protein nanoparticles
immunoglobulins
bioimaging
fluorescence
MRI
Language
ISSN
2642-5580
Abstract
Nanomedicine constantly broadens horizons of modern therapy and diagnostics. However, imaging nanoagents are of especial interest. Here, we report on novel, facile, and sustainable way to fabricate targeted multimodal imaging nanoparticles. Specifically, we synthesize nanoparticles using immunoglobulins and introduce nanoparticles of different nature into immunoglobulin-based matrix. We demonstrate applicability of the nanoparticles both in vitro and in vivo.