학술논문

Fabrication and test of implantable thin-film electrodes for stimulation and recording of biological signals
Document Type
Conference
Source
1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Microtechnologies in medicine and biology Microtechnologies in Medicine and Biology, 1st Annual International, Conference On. 2000. :619-623 2000
Subject
Components, Circuits, Devices and Systems
Bioengineering
Fabrication
Testing
Transistors
Electrodes
Microelectrodes
Polyimides
Biological tissues
Sandwich structures
Silicon
Dry etching
Language
Abstract
The fabrication, characterization and application of polyimide-based flexible microelectrodes for recording from and stimulation of biological tissue are described. The planar electrodes consist of a polyimide-platinum-polyimide sandwich structure with a total thickness of 10 to 40 /spl mu/m fabricated on Pyrex or silicon wafers. Several designs with mono-polar or multi-polar probe-type electrodes have been realized. Two different fabrication technologies using photosensitive (PS-PI) and non-photosensitive polyimide (NPS-PI) have been developed. For the photostructurable polyimide a three-mash process was realized, whereas for the non-photosensitive polyimide a simpler two-mask process using dry etching techniques was used. A sacrificial layer of aluminum served for detachment of the structures by anodic metal dissolution. This is a particularly biocompatible release procedure as the microelectrodes are detached from the fabrication substrate in a sodium salt solution. Obtained microelectrodes were characterized by impedance spectroscopy and were used to record multi-channel EMG signals from free-walking insects.