학술논문

System Calibration for FastSPECT III: An Ultra-High Resolution CCD-Based Pinhole SPECT System
Document Type
Conference
Source
2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2017 IEEE. :1-3 Oct, 2017
Subject
Bioengineering
Components, Circuits, Devices and Systems
Computing and Processing
Nuclear Engineering
Photonics and Electrooptics
Calibration
Single photon emission computed tomography
Image reconstruction
Mathematical model
Detectors
Mice
Language
ISSN
2577-0829
Abstract
FastSPECT III is a recently developed ultra-highresolution small-animal SPECT imaging system. With 20 CCDbased intensified quantum-imaging cameras (iQID) and 250micron diameter platinum pinhole apertures, this stationary SPECT system offers $\sim 350$ microns isotropic linear resolution. This paper presents a novel system calibration method for FastSPECT III and other high-resolution stationary pinholeSPECT systems. The performance of the new system calibration method was evaluated using multi-bed-position MLEM reconstruction and helically-scanned objects. Originally designed for high-resolution rodent brain imaging to study neurological pathologies, FastSPECT III now offers whole-body mouse imaging capabilities with ultra-high spatial resolution.