학술논문
A comprehensive investigation of nutritional status and psoas muscle mass in predicting five-year survival in patients with liver transplant
Document Type
article
Source
Journal of the Formosan Medical Association, Vol 121, Iss 7, Pp 1317-1324 (2022)
Subject
Language
English
ISSN
0929-6646
Abstract
Background/Purpose: Although nutrition and sarcopenia have impacts on the surgery outcome of patients who have received living donor liver transplant (LDLT), the use of the prognostic nutritional index (PNI) or psoas muscle mass index (PMI) as an indicator for five-year survival in those patients is still unclear. Methods: A total of 138 patients receiving LDLT were followed at a medical center in Taiwan. As well as analysis of clinical factors using Cox regression, time-varying PNI and PMI values as before surgery (0) and at 3-, 6-, and 12- months after LDLT were analyzed by time-dependent Cox analysis. For those 124 patients who survived after 3 months of LDLT, the values of PNI-3m, PMI-3m and their combination were further analyzed. Results: PNI and PMI were noted to be highly associated with mortality at three months post-LDLT (PNI-3m hazard ratio [HR] = 0.89, 95% confidence interval [CI]: 0.85–0.94, p