부산대학교 도서관

Cordyceps militaris Linn. Link is a fungus with high content of bioactive substances. Cordycepin is an important ingredient that determines the medicinal quality of Cordyceps sp. In this report, we studied the effects of solvents (type of solvents and solvent: water ratio), temperature, pH, incubation time with ultrasonication and number of extraction round on the extraction effiency of cordycepin from Cordyceps militaris fruiting bodies. Our results showed that, highest extraction efficiency achieved when using ethanol: water, 2:1 (v/v) as the extraction solvent; pH of the solvent should be at 7; the optimal incubation temperature was at 55 C. Furthermore, the samples should be ultrasonicated for 6 minutes with 2 pulses of 3 minutes, vortex for 1 min and 3 mins rest between pulses.