학술논문
Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) in a Large Cohort of Relapsing-Remitting MS Patients
Document Type
article
Author
Jelena Drulović; Gordana Tončev; Čongor Nadj; Dragana Obradović; Jevto Eraković; Šarlota Mesaroš; Mirjana Čukić; Dejan Aleksić; Marko Andabaka; Jovana Ivanović; Aleksa Jovanović; Marina Kostić; Gorica Marić; Aleksandar Marković; Vanja Martinović; Aleksandra Parojčić; Stojan Perić; Lorand Sakalaš; Vesna Suknjaja; Katarina Vesić; Sofija Vojvodić; Tijana Vuković; Ralph H. B. Benedict; Tatjana Pekmezović
Source
Acta Clinica Croatica, Vol 61., Iss 1., Pp 62-68 (2022)
Subject
Language
English
ISSN
0353-9466
1333-9451
1333-9451
Abstract
Cognitive impairment is one of the most frequently reported symptoms in persons with multiple sclerosis (MS). The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) has been recommended as a standardized international screening and monitoring tool for brief cognitive assessment. The aim of our study was to assess the reliability and validity of the Serbian version of the BICAMS. A total of 500 relapsing-remitting MS (RRMS) patients and 69 age-, gender- and education- matched healthy control (HC) subjects were examined. All participants performed the BICAMS test battery, which includes the oral version of the Symbol Digit Modalities Test (SDMT), California Verbal Learning Test second edition (CVLT-II), and Brief Visuospatial Memory Test Revised (BVMTR). A randomly selected subset of patients were retested one to three weeks after baseline. Statistically significant differences between patients and HCs were evident on the SDMT and BVMTR (p