학술논문

Neutrophil-to-lymphocyte ratio predicts coronary artery lesion complexity and mortality after non-ST-segment elevation acute coronary syndrome
Document Type
article
Source
Revista Portuguesa de Cardiologia, Vol 34, Iss 7, Pp 465-471 (2015)
Subject
Diseases of the circulatory (Cardiovascular) system
RC666-701
Language
English
Portuguese
ISSN
0870-2551
Abstract
Objective: Inflammatory mechanisms are known to play an important role in coronary artery disease. The present study aimed to investigate the importance of the neutrophil-to-lymphocyte ratio (NLR) in terms of in-hospital mortality and its association with currently used risk scores in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). Methods: Three hundred and seventeen patients with NSTE-ACS were included. The patients were divided into tertiles according to their NLR values (NLR 4.5). Clinical and angiographic risk was evaluated by the SYNTAX and GRACE risk scores. Results: The GRACE risk score was significantly higher in the group with high NLR values compared to those with moderate or low NLR (161.5±40.3, 130.5±32.3, and 123.9±34.3, respectively, p 4,5). Os scores de risco clínicos e angiográficos foram avaliados pelos métodos de risco SYNTAX e GRACE. Resultados: O score de risco GRACE foi significativamente mais elevado no grupo com valores RNL elevados comparado com os grupos com RNL moderado ou baixo (161,5 ± 40,3, 130,5 ± 32,3 e 123,9 ± 34,3, respetivamente, p