학술논문
Automated identification of sequence-tailored Cas9 proteins using massive metagenomic data
Document Type
article
Author
Source
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Cas9 proteins require a target-adjacent sequence, the PAM, in order to cleave DNA. Here the authors develop a pipeline to accurately predict PAM sequences in order to facilitate the identification of Cas9s targeting specific sequences, including mutations.