학술논문

A regionally based precision medicine implementation initiative in North Africa:The PerMediNA consortium
Document Type
article
Author
Yosr HamdiMaroua BoujemaaJihenne Ben Aissa-HajFouzia RadouaniMeriem KhyattiNajah MighriMariem HannachiKais GhediraOussema SouiaiChaima HkimiMohamed Selim KammounNesrine MejriHanen BouazizMohamed Amine BeloufaHicham CharouteAbdelhamid BarakatImène NajjarHiroaki TaniguchiNatalia PietrosemoliKoussay DellagiSonia AbdelhakMohamed Samir BoubakerClaudia ChicaEtienne RouleauAbdellatif beniderAdil El-hamouchiAIT YOUNES SoniaAlia Ben KahlaAMIMER AbdelmalikAMIR Zine, charifAmira JaballahAmira LouizaAmina GIHBIDBACHIR AchouakBELABDI DjihadBELHADEF SaidBELNOUI RafikaBelarbi AyedBenchakroune NadiaBenchakroun NadiaBENINAL MeriemBENKALI RadjaBENSIHAMDI AsmaBENYOUCEF HichemBENDIMRED ThourayaBensouf NadirBENNOUI RafikaBerrazegua YosraBiskri LatefaBOUAOUNI SaidaBOUANIKA MeriemBouamra AbderezzakBouaziz HanenBoudinar Fatma ZohraBouhara SabrinaBoussouf NadirBoutayeb SaberBOUNEDJAR AddaChabati OmarCharfeddine CherineChilla DaliaChiraz MehemmaiCyrine BouabidDahnane SouadDIAB SorayaDib Hocine AdlaneDorra WiderDERRAR FawziELKEBOUB AminaEL ATTAR HichamEL FAHIME ElmostafaELHADEF DjaziaEmna FehriFarid HakkouFarida HadjamFanny MamboisseGAIS WidadGHARNAOUT MerzakGuessoum Amir NidhalHADJAM FaridaHADJ SAHRAOUIHaifa RachdiHamza YaicheHANNACHI LeilaHassan MahfoufHend BouguerraHicham El AttarHichem Ben HassineHouda FilaliHouda HarmakHouda KanaaneIchrak BenamriImane El AlamiKASSA RedaKarima BendahhouKhaoula ErrafiiKhalid El BairiKhaali WafaaKARKOURI MehdiKabbage MariaKammoun WafaKanaane HoudaKassa RedaLAOUAR NarimaneLatefa BiskriLouiza AmiraLouise MarieCharion ChevalierMALOUM NabilaMarc MonotMariem SaadiMario CamponeMehdi MradMEHDI KARKOURIMELIZI MohamedMeriem SaadiMeriem CHAHERMonia ArdhaouiMourad TALEBNadia Ben JmiaaNadia BenchakrounNajet HadhriNawel SALHINezha TaoufiqNouha JandoubiOUAHIOUNE WahibaOULDSLIMANE SalimaRafika BELNOUIRahman Amira LouizaRym BenkhalifaSaber BoutaibSaber BoutayebSamia MenifSalima OULDSLIMANESamuel ValckeSLIMANI AssiaSonia Ben NasrSonia MaatougSonia Ait YounesSouad BENCHEHIDASouad BEKOUACISouha SahraouiTali Maamar HassibaTalha SorayaTALEB MouradTERKMANI FellaTALHA SorayaTOUISI WassilaWafa KammounWahiba OUAHIOUNEYosra BerrazeguaZEMMOUR AmelZEROUAL SarahZine Charif AMIRZineb Zouafi
Source
Translational Oncology, Vol 44, Iss , Pp 101940- (2024)
Subject
Precision medicine
Equity
North Africa
Capacity building
Affordable genetic testing
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Language
English
ISSN
1936-5233
Abstract
Precision Medicine is being increasingly used in the developed world to improve health care. While several Precision Medicine (PM) initiatives have been launched worldwide, their implementations have proven to be more challenging particularly in low- and middle-income countries. To address this issue, the “Personalized Medicine in North Africa” initiative (PerMediNA) was launched in three North African countries namely Tunisia, Algeria and Morocco. PerMediNA is coordinated by Institut Pasteur de Tunis together with the French Ministry for Europe and Foreign Affairs, with the support of Institut Pasteur in France. The project is carried out along with Institut Pasteur d’Algérie and Institut Pasteur du Maroc in collaboration with national and international leading institutions in the field of PM including Institut Gustave Roussy in Paris. PerMediNA aims to assess the readiness level of PM implementation in North Africa, to strengthen PM infrastructure, to provide workforce training, to generate genomic data on North African populations, to implement cost effective, affordable and sustainable genetic testing for cancer patients and to inform policy makers on how to translate research knowledge into health products and services. Gender equity and involvement of young scientists in this implementation process are other key goals of the PerMediNA project.In this paper, we are describing PerMediNA as the first PM implementation initiative in North Africa. Such initiatives contribute significantly in shortening existing health disparities and inequities between developed and developing countries and accelerate access to innovative treatments for global health.