학술논문
Suppression of a broad spectrum of liver autoimmune pathologies by single peptide-MHC-based nanomedicines
Document Type
article
Author
Source
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
Immune response against tissue-specific antigens is a hallmark of autoimmunity. Here the authors show that a single autoantigen-based nanomedicine can ameliorate pathology in a broad range of liver autoimmunity models without impairing host defenses, suggesting organ-wide tolerization.