학술논문
Antiviral Drug–Resistant Influenza B Viruses Carrying H134N Substitution in Neuraminidase, Laos, February 2016
Document Type
article
Author
Source
Emerging Infectious Diseases, Vol 23, Iss 4, Pp 686-690 (2017)
Subject
Language
English
ISSN
1080-6040
1080-6059
1080-6059
Abstract
In February 2016, three influenza B/Victoria/2/87 lineage viruses exhibiting 4- to 158-fold reduced inhibition by neuraminidase inhibitors were detected in Laos. These viruses had an H134N substitution in the neuraminidase and replicated efficiently in vitro and in ferrets. Current antiviral drugs may be ineffective in controlling infections caused by viruses harboring this mutation.