학술논문

Association between depression and HIV treatment outcomes in a US military population with HIV infection
Document Type
article
Source
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-6 (2021)
Subject
HIV
Depression
Adherence
Antiretroviral therapy
Viral load suppression
Immunologic diseases. Allergy
RC581-607
Language
English
ISSN
1742-6405
Abstract
Abstract Background Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression. Methods Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, and self-reported adherence (SRA) were included. ART use was defined as ART initiation between 2006 and 2010, with follow-up through 2015. SRA was defined as taking 95% of ART doses and continuous ART was defined as longitudinal ART use with gaps