학술논문
Ischemic strokes revealing neurosyphilis: Study of six (6) observations at the neurology Department of the University Hospital of Conakry
Document Type
article
Author
M.L. Touré; T.H. Baldé; M.S. Diallo; G. Carlos Othon; N. Camara; S.D. Barry; M.M. Konaté; F. Sakadi; E. Lamah; B. Diallo; M. Diakité; A. Sakho; D. Camara; S. Condé; H. Madandi; V. Millimono; A.K.T. Barry; M.T. Diallo; N. Traoré; F.D. Kassa; A. Koné; I.S. Souaré; J.M. Kadji; M.H. Diallo; A. Tounkara; S.A. Rafkat; T.M. Diallo; J.F. Mara; F.A. Cissé; A. Cissé
Source
eNeurologicalSci, Vol 32, Iss , Pp 100470- (2023)
Subject
Language
English
ISSN
2405-6502
Abstract
Introduction: In sub-Saharan Africa (SSA), stroke is a major public health problem and the etiological aspects are poorly studied and documented because of under-medicalization; the syphilitic etiology is rarely mentioned. Patients and methods: We performed a retrospective study of 472 patients hospitalized for ischemic stroke between 2016 and 2021 in the Neurology Department of the University Hospital of Conakry, confirmed by neuroradiological explorations (brain CT, MRI-Angio) and a biological workup including VDRL-TPHA serological reactions in blood and CSF. Results: Syphilitic etiology was retained for six (6) patients (4 men and 2 women) with a mean age of 43 years (extremes 36 and 49 years). The clinical picture was dominated by carotid syndromes: superficial and deep sylvian syndrome, anterior cerebral artery syndrome and vertebro-basilar syndromes and one case of lacunar syndrome.The diagnosis was based on the positivity of serological reactions (VDRL-TPHA) in blood and cerebrospinal fluid (CSF) and the presence of a predominantly lymphocytic hypercellularity and a hyperproteinorachy in the CSF in the absence of any other etiology. Conclusion: These neurological vascular syndromes consecutive to a cerebral treponematous attack are often the result of a still poorly conducted management of primary and secondary syphilis in our country.