학술논문
Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Document Type
article
Author
Source
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
Tuberculosis meningitis (TBM) is a severe form of TB with limited treatment options. Here, the authors perform RNA sequencing on whole blood and on ventricular and lumbar cerebrospinal fluid (CSF) samples from pediatric patients treated for TBM to characterize the immune response and tissue damage.