학술논문
The role of bioimpedance analysis in overweight and obese patients with acute heart failure: a pilot study
Document Type
article
Author
Ana Venegas‐Rodríguez; Ana María Pello; Marta López‐Castillo; Mikel Taibo Urquía; Jorge Balaguer‐Germán; Alicia Munté; Guillermo González‐Martín; Sol María Carriazo‐Julio; Juan Martínez‐Milla; Andrea Kallmeyer; Óscar González Lorenzo; Hans Paul Gaebelt Slocker; José Tuñón; Emilio González‐Parra; Álvaro Aceña
Source
ESC Heart Failure, Vol 10, Iss 4, Pp 2418-2426 (2023)
Subject
Language
English
ISSN
2055-5822
Abstract
Abstract Aims Residual congestion at the time of hospital discharge is an important readmission risk factor, and its detection with physical examination and usual diagnostic techniques have strong limitations in overweight and obese patients. New tools like bioelectrical impedance analysis (BIA) could help to determine when euvolaemia is reached. The aim of this study was to investigate the usefulness of BIA in management of heart failure (HF) in overweight and obese patients. Methods and results Our study is a single‐centre, single‐blind, randomized controlled trial that included 48 overweight and obese patients admitted for acute HF. The study population was randomized into two arms: BIA‐guided group and standard care. Serum electrolytes, kidney function, and natriuretic peptides were followed up during their hospital stay and at 90 days after discharge. The primary endpoint was development of severe acute kidney injury (AKI) defined as an increase in serum creatinine by >0.5 mg/dL during hospitalization, and the main secondary endpoint was the reduction of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) levels during hospitalization and within 90 days after discharge. The BIA‐guided group showed a remarkable lower incidence of severe AKI, although no significant differences were found (41.4% vs. 16.7%; P = 0.057). The proportion of patients who achieved levels of NT‐proBNP