학술논문

Rigorous derivation of a Hele-Shaw type model and its non-symmetric traveling wave solution
Document Type
Working Paper
Source
Subject
Mathematics - Analysis of PDEs
35R35, 76D27, 92C10, 70K50
Language
Abstract
In this paper, we consider a Hele-Shaw model that describes tumor growth subject to nutrient supply. This model was recently studied in \cite{feng2022tumor} via asymptotic analysis. Our contributions are twofold: Firstly, we provide a rigorous derivation of this Hele-Shaw model by taking the incompressible limit of the porous medium reaction-diffusion equation, which solidifies the mathematical foundations of the model. Secondly, from a bifurcation theory perspective, we prove the existence of non-symmetric traveling wave solutions to the model, which reflect the intrinsic boundary instability in tumor growth dynamics.
Comment: 23 pages, 2 figures