학술논문
A Rare Case of COVID-19 Related Acute Necrotizing Encephalopathy With the RANBP2 Mutation in a Pediatric Patient
Document Type
Article
Author
Source
The Pediatric Infectious Disease Journal; March 2024, Vol. 43 Issue: 3 pe84-e86, 3p
Subject
Language
ISSN
08913668; 15320987
Abstract
Acute necrotizing encephalopathy (ANE) is a rare childhood neurological disorder. The familiar type of ANE (ANE1) is associated with a mutation in the RANBP2gene. Both SARS-CoV-2 and RANBP2 mutations are responsible for the manifestation of a hyper-inflammatory response that invades the central nervous system and plays a key role in the rapid progression of encephalopathy.