학술논문
Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study
Document Type
Article
Author
Mrkobrada, Marko; Chan, Matthew T.V.; Cowan, David; Campbell, Douglas; Wang, Chew Yin; Torres, David; Malaga, German; Sanders, Robert D.; Sharma, Manas; Brown, Carl; Sigamani, Alben; Szczeklik, Wojciech; Sharma, Mukul; Guyatt, Gordon; Smith, Eric E.; Agid, Ronit; Dmytriw, Adam A.; Spence, Jessica; Adunuri, Nikesh R.; Borges, Flavia K.; Short, Timothy G.; Hill, Michael D.; Saad, Feryal; Copland, Ingrid; Pettit, Shirley; Ibrahim, Quazi; Bangdiwala, Shrikant I.; Yusuf, Salim; Tsai, Scott; Sahlas, Demetrios J; Mensinkai, Arun; Sposato, Luciano A; Hussain, Sara; Yang, Steven; Siegal, Deborah; Khaw, Alexander; Mandzia, Jennifer; Simpson, Sara; Raval, Manoj; Karimuddin, Ahmer; Phang, PT; Mok, Vincent CT; Wu, William KK; Yu, Simon CH; Gin, Tony; Loh, Pui San; Liew, Mun Thing; Ramli, Norlisah; Siow, Yee Lein; Fuentes, Maite; Ortiz-Soriano, Victor; Waymouth, Ellen; Kumar, Jonathan; Sadana, Divya; Thomas, Lenimol; Kaczmarek, Bogusz; Lindroth, Heidi; Sessler, Daniel; Apolcer, Sarah; Trombetta, Amelia; Handsor, Stephanie; Dasgupta, Monidipa; Murkin, John M; Lee, Shun Fu; Devereaux, P.J.
Source
The Lancet; September 2019, Vol. 394 Issue: 10203 p1022-1029, 8p
Subject
Language
ISSN
01406736; 1474547X
Abstract
In non-surgical settings, covert stroke is more common than overt stroke and is associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after non-cardiac surgery and is associated with substantial morbidity, we know little about perioperative covert stroke. Therefore, our primary aim was to investigate the relationship between perioperative covert stroke (ie, an acute brain infarct detected on an MRI after non-cardiac surgery in a patient with no clinical stroke symptoms) and cognitive decline 1 year after surgery.