학술논문

Changes in the peripheral nervous system of laboratory animals, associated with cooling and with artificial hypothermia
Document Type
Article
Source
Bulletin of Experimental Biology and Medicine; May 1958, Vol. 45 Issue: 5 p640-643, 4p
Subject
Language
ISSN
00074888; 15738221
Abstract
Experiments were performed on rats and rabbits. It was established that changes occur in the peripheral nervous system of the heart, intestine and the articular capsule in: 1) simple decrease of the body temperature by application of ice; 2) in artificial hypothermia induced by Laborits' method, and 3) in neuroplegia induced by largactyl. These changes are manifested by: a) increased staining; b) increased roughness of the nerve fibers and their varicosity. These changes mainly affect the thick terminal fibers and nerve endings, sensory function, while slender fibers of the vessels, vegetative by function, remain unchanged. The lower the body temperature in the animals and the longer the experiment, the more pronounced the changes in the nerve fibers. The most considerable changes appeared in the animals which were cooled by means of ice. In artificial hypothermia the changes were manifested mainly by increased staining of the nerve fibers and were reversible. Experiments show that hypothermia affects the whole organism. In the peripheral nervous system it mainly has an effect on the sensory nerves. However, these changes are not specific since they are also found in other prolonged interventions.