학술논문
Whole Genome Sequencing Identifies CRISPLD2as a Lung Function Gene in Children With Asthma
Document Type
Article
Author
Kachroo, Priyadarshini; Hecker, Julian; Chawes, Bo L.; Ahluwalia, Tarunveer S.; Cho, Michael H.; Qiao, Dandi; Kelly, Rachel S.; Chu, Su H.; Virkud, Yamini V.; Huang, Mengna; Barnes, Kathleen C.; Burchard, Esteban G.; Eng, Celeste; Hu, Donglei; Celedón, Juan C.; Daya, Michelle; Levin, Albert M.; Gui, Hongsheng; Williams, L. Keoki; Forno, Erick; Mak, Angel C.Y.; Avila, Lydiana; Soto-Quiros, Manuel E.; Cloutier, Michelle M.; Acosta-Pérez, Edna; Canino, Glorisa; Bønnelykke, Klaus; Bisgaard, Hans; Raby, Benjamin A.; Lange, Christoph; Weiss, Scott T.; Lasky-Su, Jessica A.; Abe, Namiko; Abecasis, Goncalo; Albert, Christine; Palmer Allred, Nicholette (Nichole); Almasy, Laura; Alonso, Alvaro; Ament, Seth; Anderson, Peter; Anugu, Pramod; Applebaum-Bowden, Deborah; Arking, Dan; Arnett, Donna K.; Ashley-Koch, Allison; Aslibekyan, Stella; Assimes, Tim; Auer, Paul; Avramopoulos, Dimitrios; Barnard, John; Barnes, Kathleen; Barr, R. Graham; Barron-Casella, Emily; Beaty, Terri; Becker, Diane; Becker, Lewis; Beer, Rebecca; Begum, Ferdouse; Beitelshees, Amber; Benjamin, Emelia; Bezerra, Marcos; Bielak, Larry; Bis, Joshua; Blackwell, Thomas; Blangero, John; Boerwinkle, Eric; Borecki, Ingrid; Bowler, Russell; Brody, Jennifer; Broeckel, Ulrich; Broome, Jai; Bunting, Karen; Burchard, Esteban; Cardwell, Jonathan; Carty, Cara; Casaburi, Richard; Casella, James; Chaffin, Mark; Chang, Christy; Chasman, Daniel; Chavan, Sameer; Chen, Bo-Juen; Chen, Wei-Min; Chen, Yii-Der Ida; Cho, Michael H.; Choi, Seung Hoan; Chuang, Lee-Ming; Chung, Mina; Cornell, Elaine; Correa, Adolfo; Crandall, Carolyn; Crapo, James; Cupples, L. Adrienne; Curran, Joanne; Curtis, Jeffrey; Custer, Brian; Damcott, Coleen; Darbar, Dawood; Das, Sayantan; David, Sean; Davis, Colleen; Daya, Michelle; de Andrade, Mariza; DeBaun, Michael; Deka, Ranjan; DeMeo, Dawn; Devine, Scott; Do, Ron; Duan, Qing; Duggirala, Ravi; Durda, Peter; Dutcher, Susan; Eaton, Charles; Ekunwe, Lynette; Ellinor, Patrick; Emery, Leslie; Farber, Charles; Farnam, Leanna; Fingerlin, Tasha; Flickinger, Matthew; Fornage, Myriam; Franceschini, Nora; Fu, Mao; Fullerton, Stephanie M.; Fulton, Lucinda; Gabriel, Stacey; Gan, Weiniu; Gao, Yan; Gass, Margery; Gelb, Bruce; Geng, Xiaoqi (Priscilla); Germer, Soren; Gignoux, Chris; Gladwin, Mark; Glahn, David; Gogarten, Stephanie; Gong, Da-Wei; Goring, Harald; Gu, C. Charles; Guan, Yue; Guo, Xiuqing; Haessler, Jeff; Hall, Michael; Harris, Daniel; Hawley, Nicola; He, Jiang; Heavner, Ben; Heckbert, Susan; Hernandez, Ryan; Herrington, David; Hersh, Craig; Hidalgo, Bertha; Hixson, James; Hokanson, John; Holly, Kramer; Hong, Elliott; Hoth, Karin; (Agnes) Hsiung, Chao; Huston, Haley; Hwu, Chii Min; Irvin, Marguerite Ryan; Jackson, Rebecca; Jain, Deepti; Jaquish, Cashell; Jhun, Min A.; Johnsen, Jill; Johnson, Andrew; Johnson, Craig; Johnston, Rich; Jones, Kimberly; Kachroo, Priyadarshini; Kang, Hyun Min; Kaplan, Robert; Kardia, Sharon; Kathiresan, Sekar; Kaufman, Laura; Kelly, Shannon; Kenny, Eimear; Kessler, Michael; Khan, Alyna; Kinney, Greg; Konkle, Barbara; Kooperberg, Charles; Krauter, Stephanie; Lange, Christoph; Lange, Ethan; Lange, Leslie; Laurie, Cathy; Laurie, Cecelia; LeBoff, Meryl; Lee, Seunggeun Shawn; Lee, Wen-Jane; LeFaive, Jonathon; Levine, David; Levy, Dan; Lewis, Joshua; Li, Yun; Lin, Honghuang; Lin, Keng Han; Liu, Simin; Liu, Yongmei; Loos, Ruth; Lubitz, Steven; Lunetta, Kathryn; Luo, James; Mahaney, Michael; Make, Barry; Manichaikul, Ani; Manson, JoAnn; Margolin, Lauren; Martin, Lisa; Mathai, Susan; Mathias, Rasika; McArdle, Patrick; McDonald, Merry-Lynn; McFarland, Sean; McGarvey, Stephen; Mei, Hao; Meyers, Deborah A.; Mikulla, Julie; Min, Nancy; Minear, Mollie; Minster, Ryan L.; Mitchell, Braxton; Montasser, May E.; Musani, Solomon; Mwasongwe, Stanford; Mychaleckyj, Josyf C.; Nadkarni, Girish; Naik, Rakhi; Natarajan, Pradeep; Nekhai, Sergei; Nickerson, Deborah; North, Kari; O'Connell, Jeff; O'Connor, Tim; Ochs-Balcom, Heather; Pankow, James; Papanicolaou, George; Parker, Margaret; Parsa, Afshin; Penchev, Sara; Peralta, Juan Manuel; Perez, Marco; Perry, James; Peters, Ulrike; Peyser, Patricia; Phillips, Lawrence S.; Phillips, Sam; Pollin, Toni; Post, Wendy; Becker, Julia Powers; Boorgula, Meher Preethi; Preuss, Michael; Prokopenko, Dmitry; Psaty, Bruce; Qasba, Pankaj; Qiao, Dandi; Qin, Zhaohui; Rafaels, Nicholas; Raffield, Laura; Ramachandran, Vasan; Rao, D.C.; Rasmussen-Torvik, Laura; Ratan, Aakrosh; Redline, Susan; Reed, Robert; Regan, Elizabeth; Reiner, Alex; Rice, Ken; Rich, Stephen; Roden, Dan; Roselli, Carolina; Rotter, Jerome; Ruczinski, Ingo; Russell, Pamela; Ruuska, Sarah; Ryan, Kathleen; Sakornsakolpat, Phuwanat; Salimi, Shabnam; Salzberg, Steven; Sandow, Kevin; Sankaran, Vijay; Scheller, Christopher; Schmidt, Ellen; Schwander, Karen; Schwartz, David; Sciurba, Frank; Seidman, Christine; Seidman, Jonathan; Sheehan, Vivien; Shetty, Amol; Shetty, Aniket; Sheu, Wayne Hui-Heng; Shoemaker, M. Benjamin; Silver, Brian; Silverman, Edwin; Smith, Jennifer; Smith, Josh; Smith, Nicholas; Smith, Tanja; Smoller, Sylvia; Snively, Beverly; Sofer, Tamar; Sotoodehnia, Nona; Stilp, Adrienne; Streeten, Elizabeth; Sung, Yun Ju; Su-Lasky, Jessica; Sylvia, Jody; Szpiro, Adam; Sztalryd, Carole; Taliun, Daniel; Tang, Hua; Taub, Margaret; Taylor, Kent; Taylor, Simeon; Telen, Marilyn; Thornton, Timothy A.; Tinker, Lesley; Tirschwell, David; Tiwari, Hemant; Tracy, Russell; Tsai, Michael; Vaidya, Dhananjay; VandeHaar, Peter; Vrieze, Scott; Walker, Tarik; Wallace, Robert; Walts, Avram; Wan, Emily; Wang, Fei Fei; Watson, Karol; Weeks, Daniel E.; Weir, Bruce; Weiss, Scott; Weng, Lu-Chen; Willer, Cristen; Williams, Kayleen; Williams, L. Keoki; Wilson, Carla; Wilson, James; Wong, Quenna; Xu, Huichun; Yanek, Lisa; Yang, Ivana; Yang, Rongze; Zaghloul, Norann; Zekavat, Maryam; Zhang, Yingze; Zhao, Snow Xueyan; Zhao, Wei; Zheng, Xiuwen; Zhi, Degui; Zhou, Xiang; Zody, Michael; Zoellner, Sebastian
Source
Chest; December 2019, Vol. 156 Issue: 6 p1068-1079, 12p
Subject
Language
ISSN
00123692; 19313543
Abstract
Asthma is a common respiratory disorder with a highly heterogeneous nature that remains poorly understood. The objective was to use whole genome sequencing (WGS) data to identify regions of common genetic variation contributing to lung function in individuals with a diagnosis of asthma.