학술논문
Guillain-Barré syndrome in the course of EBV infection after kidney transplantation--a case report.
Document Type
Academic Journal
Author
Masajtis-Zagajewska A; Department of Nephrology, Hypertension and Kidney Transplantation, Medical University of Łódź, Łódź, Poland.; Muras K; Mochecka-Thoelke A; Kurnatowska I; Nowicki M
Source
Publisher: International Scientific Literature, Inc Country of Publication: United States NLM ID: 9802544 Publication Model: Print Cited Medium: Internet ISSN: 2329-0358 (Electronic) Linking ISSN: 14259524 NLM ISO Abbreviation: Ann Transplant Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Neurological complications are quite frequent in patients after solid organ transplantation, mostly affecting the central nervous system, and less frequently the peripheral nerves. Guillain-Barré syndrome (GBS), a reactive autoimmune disease of the nervous tissue, is the most common cause of acute polyneuropathy in adults following a viral or bacterial infection. GBS has been also linked to neurotoxic adverse effects of calcineurin inhibitors. This syndrome occurs relatively frequently in patients after bone marrow transplantation, but has been a rare complication in solid organ transplant recipients. Epstein-Barr virus (EBV) infection is relatively common in transplant recipients and in some cases may lead to neurological complications.
Case Report: In this report we present an interesting case of a patient who developed GBS in the course of EBV infection 1 year after kidney transplantation.
Conclusions: In patients with rapid development of polyneuropathy after transplantation, Guillain-Barré syndrome should be excluded.
Case Report: In this report we present an interesting case of a patient who developed GBS in the course of EBV infection 1 year after kidney transplantation.
Conclusions: In patients with rapid development of polyneuropathy after transplantation, Guillain-Barré syndrome should be excluded.