학술논문

Occupational interstitial lung diseases.
Document Type
Academic Journal
Author
Spagnolo P; Respiratory, Disease Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.; Ryerson CJ; Department of Medicine, St. Paul's Hospital, University of British Columbia and Centre for Heart Lung Innovation, Vancouver, Canada.; Guler S; Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Feary J; Department of Occupational and Environmental Medicine, Royal Brompton Hospital, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Churg A; Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada.; Fontenot AP; Department of Medicine, University of Colorado Anschutz Medical Campus Aurora, Aurora, Colorado, USA.; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus Aurora, Aurora, Colorado, USA.; Piciucchi S; Department of Radiology, G.B. Morgagni Hospital/University of Bologna, Forlì, Italy.; Udwadia Z; Hinduja Hospital and Research Center, Breach Candy Hospital, Mumbai, Maharashtra, India.; Corte TJ; NHMRC Centre of Research Excellence in Pulmonary Fibrosis, Camperdown, New South Wales, Australia.; Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.; Wuyts WA; Unit for Interstitial Lung Diseases, University of Leuven, Leuven, Belgium.; Johannson KA; Department of Medicine, University of Calgary, Calgary, Alberta, Canada.; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.; Cottin V; Department of Respiratory Medicine, National Reference Coordinating Centre for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, Lyon, France.; Université de Lyon, Université Claude Bernard Lyon 1, UMR754, IVPC, Lyon, France.
Source
Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8904841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2796 (Electronic) Linking ISSN: 09546820 NLM ISO Abbreviation: J Intern Med Subsets: MEDLINE
Subject
Language
English
Abstract
Millions of workers are exposed to substances known to cause occupational interstitial lung diseases (ILDs), particularly in developing countries. However, the burden of the disease is likely to be underestimated due to under-recognition, under-reporting or both. The diagnosis of occupational ILD requires a high level of suspicion and a thorough occupational history, as occupational and non-occupational ILDs may be clinically, functionally and radiologically indistinguishable, leading to delayed diagnosis and inappropriate management. A potential occupational aetiology should always be considered in the differential diagnosis of ILD, as removal from the workplace exposure, with or without treatment, is a key therapeutic intervention and may lead to significant improvement. In this article, we provide an overview of the 'traditional' inorganic dust-related ILDs but also address idiopathic pulmonary fibrosis and the immunologically mediated chronic beryllium disease, sarcoidosis and hypersensitivity pneumonitis, with emphasis on the importance of surveillance and prevention for reducing the burden of these conditions. To this end, health-care professionals should be specifically trained about the importance of occupational exposures as a potential cause of ILD.
(© 2023 The Authors. Journal of Internal Medicine published by John Wiley & Sons Ltd on behalf of Association for Publication of The Journal of Internal Medicine.)