학술논문
Review of evidence for treatments of acute non arteritic anterior ischemic optic neuropathy.
Document Type
Academic Journal
Author
Parthasarathi P; Department of Ophthalmology, Stanford University, Palo Alto, CA, 94303, USA. pooja195@stanford.edu.; Moss HE; Department of Ophthalmology, Stanford University, Palo Alto, CA, 94303, USA.; Department of Neurology & Neurological Sciences, Stanford University, Palo Alto, CA, 94303, USA.
Source
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8703986 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5454 (Electronic) Linking ISSN: 0950222X NLM ISO Abbreviation: Eye (Lond) Subsets: MEDLINE
Subject
Language
English
Abstract
Objective: To review treatment modalities that have been studied in acute non arteritic anterior ischemic optic neuropathy (NAION).
Methods: We performed a comprehensive literature search of English language publications in the last 5 years, with human species and NAION. Articles were reviewed to identify those that described original research on treatment of acute NAION. Study type, setting, duration, interventions, and results were extracted and articles were reviewed for biases and limitations.
Results: We identified 22 kinds of treatment varying by compound and modality. These include topical, intravitreal, and systemic drugs as well as surgical approaches. Evidence for efficacy ranges from expert opinion to randomized control trials.
Conclusions: Although several treatments are utilized in practice, none of these have high quality evidence of efficacy to improve visual outcomes. Continued collaborative research is necessary to complete high quality studies in order identify effective therapies for this rare and blinding disease.
(© 2024. The Author(s), under exclusive licence to The Royal College of Ophthalmologists.)
Methods: We performed a comprehensive literature search of English language publications in the last 5 years, with human species and NAION. Articles were reviewed to identify those that described original research on treatment of acute NAION. Study type, setting, duration, interventions, and results were extracted and articles were reviewed for biases and limitations.
Results: We identified 22 kinds of treatment varying by compound and modality. These include topical, intravitreal, and systemic drugs as well as surgical approaches. Evidence for efficacy ranges from expert opinion to randomized control trials.
Conclusions: Although several treatments are utilized in practice, none of these have high quality evidence of efficacy to improve visual outcomes. Continued collaborative research is necessary to complete high quality studies in order identify effective therapies for this rare and blinding disease.
(© 2024. The Author(s), under exclusive licence to The Royal College of Ophthalmologists.)